Route 66 in Missouri

Missouri offers one of the most scenic and diverse stretches of Route 66, winding through the Ozark Mountains from St. Louis in the east to Joplin near the Kansas border. This section of the Mother Road is packed with historic landmarks — including the Wagon Wheel Motel in Cuba, the Munger Moss Motel in Lebanon, and Gary’s Gay Parita Sinclair Station in Paris Springs. The Missouri alignment passes through charming small towns, crosses the old Chain of Rocks Bridge, and follows winding two-lane roads through forested hills that feel worlds away from the interstate. Whether you’re looking for classic motels, roadside Americana, or just want to drive a beautiful stretch of American highway, Missouri’s Route 66 delivers. This section covers all the must-see attractions, towns, and stops along the Show-Me State’s portion of the historic route.